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"Oritavancin is afast acting antibiotic that can kill bacteria in 15 minutes, whereas vancomycintakes 6 24 hours. Vancomycin works by disrupting vital processes in bacteria sothey slowly stop functioning and die. Although oritavancin is a modifiedversion of vancomycin, the new study suggests that it kills bacteria in acompletely different way. "Oritavancinmolecules are good at sticking together to form clusters, which fundamentallychanges how they kill bacteria," explains Dr Ndieyira. "When two clustersdig into a bacterial surface they push apart from each other, tearing thesurface and killing the bacteria. Remarkably, we found that conditions at thebacterial surface actually encourage clustering which makes antibiotics evenmore effective. "The teamdeveloped a detailed mathematical model to describe how antibiotics behave atthe surface of bacterial cells. The model could be used to screen promising newantibiotics, identifying new drugs that can kill bacteria by using brute force. "Ourfindings will help us not only to design new antibiotics but also to modifyexisting ones to overcome resistance," says Dr Ndieyira. "Oritavancinis just a modified version of vancomycin, and now we know how thesemodifications work we can do similar things with other antibiotics. This willhelp us to create a new generation of antibiotics to tackle multi drugresistant bacterial infections, now recognized as one of the greatest globalthreats in modern healthcare.
College Course Quiz
25. If you use the computer a lot, you should take regular breaks. Once a headache starts, try taking a five minute break by closing your eyes. You may want to apply a cool compress on the forehead. This may ease the headache by regulating blood flow to the head. Keep re applying the cool compress as needed. Stress is a common cause of headache. If your headache is brought on by stress, you should learn to de stress. One way is through meditation. Sit in a quiet room to meditate. Focus on your breathing and when your thoughts wander, bring your awareness back to the present.